Drug-Nutrient Interactions

OMEPRAZOLE Also indexed as: Losec®, Prilosec®

Interactions with Nutritional Supplements

Folic acid Folic acid is needed by the body to utilize vitamin B12. Antacids, including Omeprazole, inhibit folic acid absorption. Those taking antacids are advised to supplement with folic acid.

Vitamin B12 Omeprazole interferes with the absorption of vitamin B12 from food (though not from supplements) in some studies. The fall in vitamin B12 status may result from the decrease in stomach acid required for vitamin B12 absorption from food, caused by the drug. However, all those taking Omeprazole need to either supplement with vitamin B12 or have their vitamin B12 status checked.

Ranitidine Also indexed as: Zantac®

Interactions with Nutritional Supplements

Folic acid Folic acid is needed by the body to utilize vitamin B12. Antacids, including ranitidine, inhibit folic acid absorption. Those taking antacids are advised to supplement with folic acid.

Iron Stomach acid may facilitate iron absorption. Ranitidine reduces stomach acid and is associated with decreased dietary iron absorption. Iron levels in the blood should be checked with lab tests.

Magnesium In healthy volunteers, a magnesium antacid, taken with ranitidine, decreased ranitidine absorption by 20%–25%. This interaction can be avoided by taking ranitidine two hours before or after any magnesium-containing antacids, including magnesium in vitamin/mineral supplements.

Vitamin B12 Stomach acid is needed to release vitamin B12 from food so it can be absorbed by the body. Ranitidine reduces stomach acid and is associated with decreased dietary vitamin B12 absorption. The vitamin B12 found in supplements is available to the body without the need for stomach acid. Lab tests can determine vitamin B12 levels.

Interactions with Other Compounds

Tobacco (Nicotiana species) A study of 18 healthy people found smoking decreased the acid blocking effects of Ranitidine.

Cisapride Also indexed as: Propulsid®

Interactions with Foods and Other Compounds

Alcohol Alcohol consumption interferes with Cisapride therapy.

Tobacco Smoking interferes with Cisapride therapy.

© Vicki Martin, Nutrition and Herbal Technical Consultant, Healtheries of New Zealand Limited. Used with permission.

  • Is there are support sight for adults, please

  • Just bumping this to the top of the page:

    Please do not advertise on our page. This is for sharing our experiences about Infant Reflux/GOR/GORD. If you would like us to link to your organisation or your page, please message the page. The GRSNNZ Committee will make the decision once you have provided us with information on the Governance of the Organisation, Source of your Information or your relevant NZ Health or Nutrition Qualification etc. Grumble over...

  • Here is a new post to our page:

    Hello to All the Mum's.. Soo glad i found this page.. Have a 16 month old lil baby boy who has very bad reflux.. He throws up 90% of what he eats.. Im at my wits end.. Wana just burst into tears when he throws up now.. He hates any thing on his tongue.. Eg.. If he drinks milk or eats something and while playing has to get a lil piece of hair or fluff in his mouth.. He gets nauseous and throws up EVERYTHING!! Has anyone experienced this? Paed had put him on Nexiam 2 weeks ago but no improvement since.. Pls help me💔

  • Hello to All the Mum's.. Soo glad i found this page.. Have a 16 month old lil baby boy who has very bad reflux.. He throws up 90% of what he eats.. Im at my wits end.. Wana just burst into tears when he throws up now.. He hates any thing on his tongue.. Eg.. If he drinks milk or eats something and while playing has to get a lil piece of hair or fluff in his mouth.. He gets nauseous and throws up EVERYTHING!! Has anyone experienced this? Paed had put him on Nexiam 2 weeks ago but no improvement since.. Pls help me💔

  • http://www.pinkymckay.com/how-can-i-get-my-baby-to-sleep-more-than-45-minutes/

      “I’m after some advice on how to get my baby to sleep longer than 45 minutes during the day. it seems to be a common topic with many mummies and i wondered whether you had already blogged this and if so if you could point me in the right direction to find it. Alternatively if you havent, do you th…

  • http://www.treasures.co.nz/Explore-your-stage/Article/?contentId=1784920 These won't work if your child is unwell or in pain, but are otherwise good tips.

    Sleeping through the night At this age and stage research by Dr Marc Weissbluth indicates that hunger is no longer why your baby is waking at night if they are a healthy weight and continuing to gain weight we can teach them to sleep from 7pm-7am. Your baby needs to be eating a healthy diet of carbo…

  • Hi everyone, It has been pointed out that new posts to the page by non-admin don't show up in your newsfeed. I don't want to repost them, but if you want to pop on over and share your experiences there are a few new posts from October.

  • Please do not advertise on our page. This is for sharing our experiences about Infant Reflux/GOR/GORD. If you would like us to link to your organisation or your page, please message the page. The GRSNNZ Committee will make the decision once you have provided us with information on the Governance of the Organisation, Source of your Information or your relevant NZ Health or Nutrition Qualification etc. Grumble over...

  • https://www.healthed.govt.nz/system/files/resource-files/HE2309.pdf Cool pictures, lovely mothers. Not saying that women who choose to bottle feed aren't wonderful mothers too, but this is neat promotion.

  • Hi there. Posting from the UK. Wanted to share our story to gain some more insight. We've had a really tough time. My first baby is 8 + weeks now and we've had no end of issues. She was tongue tied..snipped...but latch still a problem. She is mostly breastfed but using nipple shields. Occasional top up when i can't tolerate feeding her. She feeds or wants to feed constantly. Thought it was hunger but no different after a bottle of formula. Anyway...a friend mentioned she could have silent reflux...symptoms are constant feeding hand sucking...back arching fussing through feeds like she wants it but doesn't too. Struggles to sleep although sooo tired. Falls asleep on boob but wakes immediately after. Hiccups a lot. Sneezes a lot. Crys after feeds...weight has been slow to gain tho. Prescribed infant gaviscon...any experiences of this and is it likely to make her constipated if mostly breastfed?! Worried it feels like trial and error at her expense. She's so unsettled and we are really struggling....opinions welcome :)

  • The Cards are now available in an app for Android and Apple devices: http://allright.org.nz/our-projects/tiny-adventures/

    Our Pack of Tiny Adventures was developed to help parents to enjoy quick, fun and affordable activities with their children. It was developed in partnership with SKIP (Strategies with Kids Information for Parents) gives parents easy ways to connect with their kids - even if they only have a few min…

  • My 12 week old baby has reflux, currently on 5mg of losec in the morning novelac reflux formula, she also suffers with painful wind, lately she has been choking on her vomit, not sure if I should change to novo lac colic formula instead, we have tried soy and goats to which she spewed up a lot more than the ar formula, please help with suggestions , it is hugely stressful for our family

  • Cn u get formula made for babies with reflux on script?

  • I'm getting the September Newsletter ready. Is there anything anyone wants to contribute? Please let me know: https://www.facebook.com/roslyn.ballantyne.rn

  • Hi there are there any formulas that you can get on prescription or financial assistance? Pretty sure my 8 week old isn't coping with his formula that he's on. He has reflux and on ranitidine but now he has green mucousy poo so im thinking he might need some different formula? But I see specialist formulas are expensive!!

  • Hi, my 5 month old has started solids and we have been ok'd to feed these before milk as otherwise he spills most of it. He takes losec granules, which was have been giving with pear 30mins before a milk feed. Can we now just give these with his solids with milk following half an hour+ later? Or not due to the higher volume of food in his stomach so it wouldn't be digested by the time he has his milk. Thanks